Nutraceuticals 2004

Stephen Holt M.D.,MRCP, FRCP, FACG, FACP, FACN, FACAM
Natures Benefit, Inc. Holt MD Labs Syndrome X Inc.
www.naturesbenefit.com

A REVOLUTION IN MEDICINE
. Questioning allopathic medicine
. Increased self-reliance of patients
. Portability of healthcare
. The pharmaceutical revolution
. DSHE Act, 1994
. Identifying the first line option
. Prevention vs. treatment
. Edutherapy

DIETARY SUPPLEMENTS
. Evidence-based
. Borrowed science
. Bioequivalence
. Pharmaceutical sciences
. Who owns the intervention?

PUBLIC HEALTH INITIATIVES
. The obesity pandemic
. Obesity-related disease
. The Metabolic Syndrome X
. Menopause management
. Osteoporosis
. Sleeplessness
. Digestive disorders
. Cancer prevention

THE OBESITY PANDEMIC
. Global
. Low carb diet craze
. Diabesity
. Obesity-related disease

DIABESITY

A LITANY OF DIETS
. ATKINS’ DIET
. ZONE DIET
. CARBOHYDRATE ADDICTS DIET
. SOUTH BEACH DIET
. SUGARBUSTERS DIET
. BEYOND ATKINS

ENHANCING LOW CARB DIETS
. Lifestyle change
. Exercise
. Behavior modification
. Rough calorie counting
. Dietary supplements that combat insulin resistance and components of Syndrome X
. New “diet revolution” has health initiative

SYNDROME X PREVALENCE US ADULTS
ATP 111, JAMA, Jan 16, 2002
. 8814 Participants
. Data 1988-1994 with 2000 census data
. 47 million US residents with Syndrome X

Forbes Magazine, August 6, 2001
. 70 million Americans with Syndrome X
. Children – 2% prevalence ?

THE PUBLIC HEALTH RISK
. Syndrome X increases risk for :
Maturity Onset Diabetes
Mellitus
Cardiovascular Disease
Cardiovascular Deaths
Deaths from ALL CAUSES
Am.J.Epidemiol , 148, 958, 1998 .

INTEGRATED MEDICINE FOR SYNDROME X
“While proper management of the individual abnormalities of this syndrome can reduce morbidity and mortality, it seems unlikely that management of the individual abnormalities of this syndrome provides better outcomes than a more integrated strategy,” – CDC, Atlanta, Ga.

THE X FACTORS
. Insulin resistance
. Obesity
. High blood LDL
. Low blood HDL
. Slow clearance of fats from blood
. Cholesterol synthesis in the liver
. Blood clotting
. Adverse lifestyle
. Serum uric acid
. Homocysteine

GLUCOSE TOLERANCE WITH SOLUBLE FIBER THE PHYSIOLOGICAL BASIS OF THE GLYCEMIC INDEX

Holt S, et al
Effect of Gel Fiber.
Lancet,
March 24 th , 1979.

GLUCOSE TOLERANCE WITH SOLUBLE FIBER SLOW SUGAR ABSORBTION BY STOPPING STOMACH EMPTYING

Holt S, et al
Effect of Gel Fiber.
Lancet,
March 24 th , 1979.

SUPER-SIZING AMERICA

. Americans exude complacency about their overweight status
. Obesity is part of a metabolic syndrome
. Syndrome X is under diagnosed and often mistreated by conventional medicine

SYNDROME X NUTRITIONAL FACTORS

SYNDROME X NUTRITIONAL FACTORS

SYNDROME X NUTRITIONAL FACTORS

MENOPAUSE MANAGEMENT
. 47 million confused mature females
. Benefits of HRT outweighed by risks
. Menopause does not fit disease model
. Naïve notion of estrogen deficiency

HRT
. Cardiovascular risk
. Cancer promotion
. Cognitive decline
. Quality of life

EVIDENCE-BASED, FIRST LINE MENOPAUSE MANAGEMENT
. Lifestyle adjustment
. Symptomatic improvement
. Combat onslaught of post-menopausal disease
. Cardiovascular disease
. Age-related cancer
. Cognitive decline
. Osteoporosis

EVIDENCE-BASED, COMBINATION SUPPLEMENT
. Black cohosh
. Soy isoflavones
. L- theanine
. Evening primrose oil
. Dong quai
. Chasteberry
. Gingko biloba
. Synergy: Combinations

OSTEOPOROSIS
. Lifestyle
. Calcium is not enough
. Complex formulations for nutritional support:
calcium, soy isoflavones , ipriflavone , D3, zinc, copper, manganese, boron, antioxidants
B6, B12, folic acid
. Action today for health tomorrow

SLEEP NATURALLY
. Lifestyle
. Hypnotic drugs are dangerous and addictive
. Nutritional support: Complex formulations
Valerian, chamomile, passion flower, lemon balm, skullcap, hops, ashwagandha
5 HTP, magnesium, melatonin, niacin, B6, folate

GI SUPPLEMENTS
. Pooping for health
. Enzymes
. Probiotics
. Prebiotics
. Detox
. Acid-related disorders

REAL ADVANCES IN GI
. Combining prebiosis , probiosis , detox with enzymes
. Biphasic neutralization or inhibition of acid secretion: natural acid neutralization, natural proton-pump inhibition

ZANASEC
. Patented, natural neutralization with fava bean flour, calcium, magnesium
. Proton-pump inhibition: Murakami S, et al Inhibition of gastric H + , K + – ATPase . Planta Med, 57 (1991)
. Anti-H. pylori

CANCER PREVENTION
. Antioxidants
. Lipo -hydro access
. Redox balance
. Independent power
. Green tea
. Ellagic acid
. Resveratrol

CONCLUSION
. Lifestyle change, good nutrition and well-planned dietary supplements or “functional foods” are first line options for prevention and, at least, complementary management of disease
. Advances in nutraceutical medicine may have more to offer than the next “me-too” drug

Spread the word. Share this post!

Leave A Reply